The LONI Java Image I/O plugins give Java programmers easy access to the metadata and image data stored in many common file formats (AFNI, ANALYZE, DICOM, ECAT, GE, INTERFILE, MINC, and NIFTI) produced by scanners and neuroimaging software. Following the Java Image I/O API Specification, all metadata is represented as XML DOM trees and all images are returned using the same standard class. Read and write AFNI, ANALYZE 7.5, DICOM, ECAT 7.2, GE 5.0, INTERFILE (including hrrt), MINC, NIFTI, and UCLA PACS file formats.